IGF-1 LR3 1 mg — Lyophilized Vial 1 mg · 1 vial

What is IGF-1 LR3?

IGF-1 LR3, or Long R3 IGF-1, is a modified analog of insulin-like growth factor 1. It is designed to interact differently with IGF-binding proteins while retaining activity at the IGF signaling system.

Biological activity

Reduced binding to some IGF-binding proteins can change how much analog is available to act on cells. Experiments have examined receptor activity, protein synthesis and proliferation. These findings should not be simplified into a universal potency multiplier or a fixed human duration of action.

Purpose and areas of study

Researchers use the analog to distinguish direct IGF-receptor signaling from the effects of binding proteins in cell-growth and metabolism experiments. It is relevant to studies of how growth factors regulate cellular responses.

Evidence context

Cell and animal findings do not establish a human muscle-building treatment or a universal potency multiplier.

Product presentation

One lyophilized vial. Labeled content: 1 mg.

Scientific references

PubMed 1378742; PubMed 7683526

Research-use information

All information on this page is provided for scientific education and research purposes only. This product is intended exclusively for laboratory research and is not for human or veterinary use. The information is not medical advice or a claim of therapeutic benefit.